Renal Radionuclide Tracers

Glomerular Filtration Agents

99mTc-DTPA (diethylenetriamine pentaacetic acid)

1. >90% glomerular filtration

Tubular Secretion Agents

99m-Tc MAG3 (mercaptoacetyltriglycine)

1. >95% cleared by proximal tubules

Tubular Bound Agents

99m-Tc DMSA (dimercaptosuccinic acid)

1. 40% cortical binding

Tubular Binding and Glomerular Filtration

99m-Tc Glucoheptonate

1. 10-20% tubular retention at 1-2 hours
2. 80-90% glomerular filtration